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So the archaeal RNase P RNAs were apparently "defective" compared to those of Bacteria. The obvious question, then, is "What differences in the structures of these RNAs is the cause of the difference in their protein-dependence?" So we began an in-depth comparative analysis of the structure of the archaeal RNase P RNA so that we could compare them to those of Bacteria. The distillation of quite a lot of work cloning and sequencing RNase P RNA-encoding genes from a wide range of Archaea, then aligning and analyzing these sequences, is shown above; the high-resolution secondary structures of the two original archaeal RNase P RNAs, those of H. volcanii and S. acidocaldarius.