<< Start | < Previous slide | Slide 23 | Next slide > | End >>

It turns out the Archaea have a potential homolog of another eukaryotic RNase P protein, human Rpp25. This protein is not found in all eukaryotes - it's not present in yeast, for example - but the evidence for it being an RNase P subunit in humans looks pretty good.

Jeff Barnes, an MS student in my group, has produced antiserum against the homolog of Rpp25 in M.thermoautotrohpicum, Mth1483. Experiments exactly like those I showed before for Mth11, 11618, 687, and 688 provide no evidence that Mth1483 is a subunit of RNase P.